Challenge by a nonadapted powdery mildew fungal pathogen leads to the formation of a local cell-wall apposition (papilla) beneath the point of attempted penetration.Several plasma membrane (PM) proteins with opposing roles in powdery mildew infection, including Arabidopsis thaliana PENETRATION1 (PEN1) Disney and barley (Hordeum vulgare) MILDEW RESI
Discovery and cardioprotective effects of the first non-Peptide agonists of the G protein-coupled prokineticin receptor-1.
Prokineticins are angiogenic hormones that activate two G protein-coupled receptors: PKR1 and PKR2.PKR1 has emerged as a critical mediator of cardiovascular homeostasis and cardioprotection.Identification of non-peptide PKR1 agonists that contribute to myocardial repair and collateral vessel growth hold promises for treatment of heart diseases.Thro